Gentamicin Improvement Project

Doctor unpackaging syringe.

Small Difference between Optimal and Toxic Dosing

Gentamicin is the seventh most commonly used antibiotic in Irish hospitals, given to approximately 15,000 patients per annum.

It is a potentially life-saving drug, used to treat Gram-negative infections in some of the sickest patients in our hospitals.

However Gentamicin has a narrow therapeutic index. This means that there is only a small difference between optimal and toxic dosing.

Failure to achieve optimal dosing can lead to increased patient morbidity and mortality, and increased resistance. Overdosage can cause temporary or permanent kidney damage, loss of hearing or balance disturbance.

Join the Gentamicin Improvement Project

As part of the National Quality Improvement Programme, this project aims to improve Gentamicin usage within hospitals across Ireland. So far the group has published a Gentamicin Improvement Guide and is in the process of publishing guidelines for Gentamicin usage.

If you are interested in joining this project come to our next meeting on 27 September 2016 at 4:30pm. 

To RSVP, please contact us at the contact details listed below.

Doctor and trainee.

Start Using Our Gentamicin Improvement Guide

This guide is aimed at hospitals that want to ensure the safety and efficacy of Gentamicin, a powerful but potentially toxic antibiotic.

Developed by frontline clinicians, support staff and national quality improvement experts, the guide is essentially an aid to direct hospitals through the process of improving the quality of prescribing and usage of Gentamicin.

It covers all stages of the quality improvement journey:

  • Establishing structure
  • Establishing an aim
  • How to start measuring
  • How to start making changes

Gentamicin Improvement Guide

Facing the Challenge Of Gentamicin Usage

This improvement guide will aid you through the process of improving the quality of prescribing and usage of Gentamicin.

Other Important Documents

How to Use Driver Diagrams

A driver diagram is an improvement tool that helps to ‘drive’ the path of your project.

It provides a visual representation of your project, clearly defining the aim, primary drivers and secondary drivers. The aim is devised using the SMART aim template.

How to Use Run Charts

Creating a Runchart

A runchart is a process analysis tool. It is a graph of data over time which enables you to see patterns and whether improvements are happening.

How to Create a SMART Aim Statement

A SMART aim statement is an explicit statement which describes what a successful project is expected to achieve. ‘SMART’ is an acronym for Specific, Measurable, Applicable, Realistic, and Timely.

How to Create a Stakeholder Map

A stakeholder map is a project management tool that helps to identify all of the stakeholders involved in or impacted by a project and sorts them according to their impact on the project and the impact of the project on them.

Doctor and trainees talking.

Better Patient Outcomes

By following the advice in this improvement guide, hospitals may see the following benefits:

  • better patient outcomes in treating Gram negative sepsis, including potentially reduced mortality
  • reduced need to escalate to broader spectrum antibiotics, thereby preserving their utility for more complex infective cases
  • reduced time spent in hospital due to sub-therapeutic use of Gentamicin
  • reduced rates of harm from inappropriate use
  • fewer patients requiring Nephrology or Critical Care referral
  • potentially reduced costs associated with harm from Gentamicin, including reduced direct treatment costs, renal replacement therapy costs and litigation costs
  • potentially reduced length of stay for patients treated with Gram-negative sepsis.

It should be noted that this guide relies on appropriate patient selection. Careful consideration of the potential risks and benefits should occur for every patient. This risk assessment should continue throughout therapy.

 

Quarterly Check-in Meetings to Discuss Progress

Anyone using the Gentamicin Improvement Guide is invited to attend or dial into our quarterly meetings. At these meetings teams who are using the guide discuss their progress and can get additional advice on improvement.

The next meeting is on Tuesday 27 September 2016 at 4:30pm. Please contact Vicky Taylor to confirm your attendance.

Contact Us

Victoria Taylor

Executive, Healthcare Quality Improvement

Tel: + 353 1 863 9780

Victoria is the Quality Executive and works on many of our Quality Improvement Programmes. Contact Victoria for more information on any of our healthcare quality improvement programmes.